Thursday, October 22, 2015

Living Donor Organ Transplantation








Living Donor Organ Transplantation
Buku Ini   adalah buku diterbitkan tahun 2008  McGraw-Hill Companies, Inc. USA adalah buku edisi Pertama.



Judul:   Living Donor Organ Transplantation
Oleh:    Rainer W.G. Groessner et al (Editor)
Penerbit:  McGraw-Hill Companies, Inc. USA
Tahun: 2008
Jumlah Halaman:  855  hal.


Editor:
Rainer W.G. Gruessner, MD

University of Arizona, Tucson
Enrico Benedetti, MD
University of Illinois, Chicago

Lingkup Pembahasan:
Buku ini merupakan upaya bersama antara divisi transplantasi di Universitas Minnesota, Minneapolis, dan University of Illinois, Chicago. Keduanya telah melakukan transplantasi donor hidup dari semua organ perut; 1 dari 2 lembaga ini juga telah melakukan pulau donor hidup dan transplantasi paru-paru. Sejak tahun 2002, 2 divisi transplantasi donor hidup ini melakukan transplantasi organ perut, diadakan setiap tahun. 3 konferensi diadakan sejauh dibawa bersama-sama dibedakan sarjana dari Asia, Eropa, dan Amerika Utara. Proses dari 2004dan 2006 konferensi diterbitkan dalam literatur peer-review,  transplantasi 2 divisi untuk menghasilkan buku ini.
Tujuan dari editor adalah untuk merakit kontribusi ilmiah dari  para ahli yang paling terkenal  dalam bidang ini, termasuk orang-orang yang telah merintis aspek prosedur bedah donor hidup. Kami merasa terhormat bahwa Dr Murray, dalam kata pengantarnya, dijelaskan awal pengalaman dengan transplantasi ginjal donor hidup. Kami juga berterima kasih kepada Dr Francis Delmonico yang, dalam kapasitasnya sebagai presiden dari Jaringan Serikat untuk Organ Sharing dari Juni 25, 2005, hingga 30 Juni 2006, disorot 2 state-of-the-art pertemuan pada donor hidup transplantasi bahwa ia telah terorganisir. Pertemuan pertama, diadakan di Amsterdam pada bulan Desember 2004, difokuskan pada perawatan hidup donor ginjal; pertemuan kedua, yang diadakan di Vancouver di September 2005, difokuskan pada perawatan paru-paru hidup, hati, pankreas, dan donor usus.

Buku ini terdiri atas 4 bagian. 4-bagian buku ini dirancang untuk memberikan gambaran tentang transplantasi donor hidup. Berbagai topik prosedural menyentuh, dari konseling donor dan
insentif keuangan kepada penerima pemeriksaan dan hasil. Berbagai topik prosedural menyentuh, dari konseling donor dan insentif keuangan kepada penerima pemeriksaan dan hasil. Refleksi pribadi pelopor transplantasi menawarkan latar belakang sejarah, sementara perhatian yang cukup juga dibayar untuk kemungkinan masa depan dalam bidang  yang selalu berubah. Masalah bedah dan medis spesifik untuk donor perut  transplantasi organ hidup dibahas secara rinci, memberikan banyak informasi untuk kedua pemula dan ahli.
Target utama buku ini meliputi ahli bedah transplantasi dan dokter, bersama dengan para peneliti di medan terkait seperti nefrologi, hepatologi, gastroenterologi, endokrinologi, patologi, imunologi, radiologi, dan etika. Sebuah referensi  kognitif kerja, juga akan menarik bagi rekan-rekan transplantasi, warga, mahasiswa kedokteran, koordinator, perawat, dan pekerja sosial, serta administrator rumah sakit dan profesional medis lainnya.


Daftar isi:
FOREWORD xv
    Joseph E. Murray, MD
PREFACE xvii
    Rainer W.G. Gruessner, MD, Enrico Benedetti, MD
COMMENTARY: THE AMSTERDAM AND VANCOUVER xxix
CONFERENCES ON LIVING ORGAN DONATION
    Francis L. Delmonico, MD

PART I: GENERAL ASPECTS OF LIVING DONOR ORGAN TRANSPLANTATION
CHAPTER 1 INTRODUCTION AND RATIONALE 3

    Rainer W.G. Gruessner, MD, Sarah Taranto, BA, Angelika C. Gruessner, PhD
CHAPTER 2 CULTURAL DIFFERENCES IN LIVING ORGAN DONATION: A GLOBAL PERSPECTIVE 6
    Clive O. Callender, MD, Micean Johnikin, MS, Patrice Miles
CHAPTER 3 ETHICAL AND LEGAL ISSUES 16
    3.1   THE AMERICAN PERSPECTIVE 16
             David C. Cronin II, MD, PhD, Mark Siegler, MD
    3.2   THE ASIAN PERSPECTIVE 23
    3.3   THE EUROPEAN PERSPECTIVE 37
            Thomas Gutmann, PhD, MA, Walter G. Land, MD
CHAPTER 4 DONOR COUNSELING AND CONSENT 43
    4.1   TEACHING AND TESTING THE KNOWLEDGE AND THINKING OF LIVING ORGAN
            DONORS  43
            Ro ert W. Steiner, MD, Christine A. Frederici, LCSW, Rodolfo R. Batarse, MD, Bernard
            Gert, PhD
    4.2   INFORMED CONSENT 47
            Aaron Spital, MD
    4.3   DONOR ADVOCACY 54
            David M. Kashmer, MD, Tim Schmitt, MD, Ken Brayman, MD, PhD
CHAPTER 5 NONDIRECTED AND CONTROVERSIAL DONORS 57
    Arthur J. Matas, MD
CHAPTER 6 SOCIAL ISSUES 64
    Thomas R. McCune, MD

PART II: PAID LEGAL AND ILLEGAL ORGAN DONATION
CHAPTER 7 CURRENT FINANCIAL INCENTIVES 73
    7.1  INCENTIVES IN WESTERN COUNTRIES: THE WISCONSIN MODEL 73
           Steve Wieckert, Scott Becher, Hans W. Sollinger, MD, PhD
    7.2  INCENTIVES IN NON-WESTERN COUNTRIES: THE IRANIAN MODEL 75
           Ahad J. Ghods, MD
CHAPTER 8 PAID LEGAL ORGAN DONATION 81
    8.1  PRO: THE CLINICIAN’S PERSPECTIVE 81
           Arthur J. Matas, MD
    8.2  PRO: THE PHILOSOPHER’S PERSPECTIVE 88
           Janet Radcliffe-Richards, BA, MA, Bphil
    8.3  CON: THE CLINICIAN’S PERSPECTIVE 94
           Francis L. Delmonico, MD
    8.4  CON: THE ETHICIST’S PERSPECTIVE 98
        Jeffrey Kahn, PhD, MPH
CHAPTER 9 CHALLENGES OF PAID ORGAN DONATION FOR PUBLIC HEALTH CARE POLICY     100
    Mark J. Cherry, PhD
CHAPTER 10 ILLEGAL ORGAN TRADE: GLOBAL JUSTICE AND THE TRAFFIC IN HUMAN ORGANS 106
    Nancy Scheper-Hughes, PhD
CHAPTER 11 THE IMPACT OF THE INTERNET ON PAID LEGAL AND ILLEGAL ORGAN DONATION 122
    W. Ben Vernon, MD

PART III: ORGAN-SPECIFIC ASPECTS OF LIVING DONOR ABDOMINAL ORGAN TRANSPLANTATION

SECTION I KIDNEY TRANSPLANTATION
CHAPTER 12 KIDNEY TRANSPLANTATION: PERSONAL REFLECTIONS 131

    John S. Najarian, MD
CHAPTER 13 HISTORY OF LIVING DONOR KIDNEY TRANSPLANTATION 133
        Luis H. Toledo-Pereyra, MD, Alexander Horacio Toledo, MD
CHAPTER 14 KIDNEY TRANSPLANTATION: GEOGRAPHICAL DIFFERENCES 139
    Roberts S. Kalil, MD, Lawrence G. Hunsicker, MD
CHAPTER 15 KIDNEY TRANSPLANTATION: THE DONOR 144
    15.1 SELECTION AND WORKUP 144
            Mark E. Rosenberg, MD, Cathy Garvey, RN, Cheryl Jacobs, MS, LICSW
    15.2 THE MARGINAL DONOR 154
            E. Steve Woodle, MD, Mahmound El Khatib, MD
    15.3 IMMUNOLOGIC EVALUATION 158
            Andrea A. Zachary, PhD
    15.4 ANESTHESIOLOGIC CONSIDERATIONS 163
            David S. Beebe, MD
    15.5 SURGICAL PROCEDURES 165
    15.6 PERIOPERATIVE CARE OF THE KIDNEY DONOR 198
            Mark L. Sturdevant, MD, Rainer W.G. Gruessner, MD
    15.7 DONOR MORBIDITY AND MORTALITY 200
            Burak Kocak, MD, Joseph R. Leventhal, MD, PhD
    15.8 LONG-TERM OUTCOME 205
            Arthur J. Matas, MD, Hassan N. Ibrahim, MD, MS
    15.9 PSYCHOLOGICAL ASPECTS 212
            Annette Lennerling, RN, MSc, PhD
CHAPTER 16 KIDNEY TRANSPLANTATION: THE RECIPIENT 217
    16.1 SELECTION AND WORKUP 217
            Rahul Koushik, MD, Bertram L. Kasiske, MD
    16.2  ANESTHESIOLOGIC CONSIDERATIONS 224
             David S. Beebe, MD
    16.3  SURGICAL PROCEDURES 227
             Howard Sankary, MD, Enrico Benedetti, MD
    16.4  ISCHEMIA AND REPERFUSION INJURY 232
             Stefan G. Tullius, MD, Nicholas L. Tilney, MD
    16.5  PERIOPERATIVE CARE 239
             Mark L. Sturdevant, MD, Vincent Casingal, MD, Rainer W.G. Gruessner, MD
    16.6   POSTTRANSPLANT COMPLICATIONS 242
             Amer Rajab, MD, Anatolie Usatii, MD, Ronald M. Ferguson, MD, PhD
    16.7   IMMUNOSUPPRESSIVE THERAPY 252
              David Axelrod, MD, MBA, Dixon B. Kaufman, MD, PhD
    16.8   IMMUNOBIOLOGY 265
              Gunilla Einecke, MD, Philip F. Halloran, MD, PhD
    16.9   RECURRENCE OF DISEASE 271
             Abel E. Tello, MD, Hassan N. Ibrahim, MD, MS
    16.10 RETRANSPLANTATION 282
              Akinlolu O. Ojo, MD, Laura L. Christensen, MS, Fu Luan, MD
    16.11 PEDIATRIC ISSUES 287
    16.12 PREEMPTIVE LIVING TRANSPLANTATION: THE IDEAL THERAPEUTIC
              MODALITY FOR END-STAGE RENAL DISEASE   313
              Herwig-Ulf Meier-Kriesche, MD, Jesse D. Schold, MStat, MEd
    16.13 LONG-TERM OUTCOME 319
              J. Michael Cecka, PhD
    16.14 IMMUNOLOGIC ISSUES 326
              Junchao Cai, MD, PhD, Paul Terasaki, PhD
    16.15 LIVING DONOR KIDNEY TRANSPLANTATION AND MALIGNANCY   328
              E. Steve Woodle, MD, Thomas G. Gross, MD, Rita Alloway, PharmD,
              Amit D. Tevar, MD, Joseph Buell, MD
    16.16 STRATEGIES TO MAXIMIZE THE DONOR POOL 336
CHAPTER 17 KIDNEY TRANSPLANTATION: COST ANALYSIS 364
    Mark A. Schnitzler, PhD, Thomas Burroughs, PhD, Steven K. Takemoto, PhD

SECTION II PANCREAS TRANSPLANTATION
CHAPTER 18 HISTORY OF AND RATIONALE FOR PANCREAS 

TRANSPLANTATION 369
    18.1 HISTORY OF LIVING DONOR PANCREAS TRANSPLANTATION 369
            David E. R. Sutherland, MD, PhD, John S. Najarian, MD, Rainer W.G. Gruessner, MD
    18.2 RATIONALE FOR LIVING DONOR PANCREAS TRANSPLANTS 383
            Rainer W.G. Gruessner, MD
CHAPTER 19 PANCREAS TRANSPLANTATION: THE DONOR 385
    19.1 SELECTION AND WORKUP 385
            Elizabeth R. Seaquist, MD, Rainer W.G. Gruessner, MD
    19.2 SURGICAL PROCEDURES AND PERIOPERATIVE CARE   389
    19.3 MORBIDITY, MORTALITY, AND LONG-TERM OUTCOME 398
            Rainer W.G. Gruessner, MD
CHAPTER 20 PANCREAS TRANSPLANTATION: THE RECIPIENT 401
    20.1 SELECTION AND WORKUP 401
            Raja Kandaswamy, MD
    20.2 SURGICAL PROCEDURES 403
            Rainer W.G. Gruessner, MD
    20.3 PERIOPERATIVE CARE, IMMUNOSUPPRESSIVE THERAPY, AND
            POSTTRANSPLANT  COMPLICATIONS 408
            Raja Kandaswamy, MD
    20.4 THE IDENTICAL TWIN TRANSPLANT EXPERIENCE: RECURRENCE OF
            DISEASE   412
            Rainer W.G. Gruessner, MD
CHAPTER 21 REGISTRY REPORT AND LONG-TERM OUTCOME 414
    Angelika C. Gruessner, PhD
CHAPTER 22 ISLET AUTOTRANSPLANTATION AFTER PANCREATECTOMY: HISTORY AND OUTCOMES 419
    David E.R. Sutherland, MD, PhD, Takashi Kobayashi, MD, Bernhard J. Hering, MD,
    Tun Jie, MD, Annelisa M. Carlson, MD
CHAPTER 23 ISLET TRANSPLANTATION USING LIVING DONORS 429
    Juliet Emamaullee, PhD, James Shapiro, MD, PhD

SECTION III LIVER TRANSPLANTATION
CHAPTER 24 PERSONAL REFLECTIONS AND HISTORY OF LIVING DONOR LIVER TRANSPLANTATION 438

    Christoph E. Broelsch, MD, Silvio Nadalin, MD, Massimo Malagó, MD
CHAPTER 25 REGIONAL VARIATIONS IN THE U.S. LIVING DONOR EXPERIENCE 442
    Mark Wang, MD, Irma Dixler, BSN, RN, Jonathan P. Fryer, MD
CHAPTER 26 INSTITUTIONAL NEEDS FOR LIVING DONOR: LIVER 
TRANSPLANTATION   448
    Alan J. Koffron, MD, Michael Abecassis, MD
CHAPTER 27  ROLE OF SPLIT LIVER TRANSPLANTATION FROM DECEASED DONORS: LESSONS LEARNED 453
    Andrew M. Cameron, MD, PhD, Hasan Yersiz, MD, Ronald W. Busuttil, MD, PhD
CHAPTER 28 LIVER REGENERATION 459
    Jeroen de Jonge, MD, PhD, Kim M. Olthoff, MD
CHAPTER 29 LIVING DONOR LIVER TRANSPLANTATION: THE DONOR 468
    29.1 SELECTION AND WORKUP 468
            Abhinav Humar, MD, Cheryl Jacobs, MS, LICSW, Ann Kalis, RN
    29.2 ANESTHESIOLOGIC CONSIDERATIONS 475
            Suzanne Shamsolkottabi, MD, Kumar G. Belani, MBBS, MS
    29.3 SURGICAL PROCEDURES 477
    29.4 PERIOPERATIVE CARE 500
            Giuliano Testa, MD, Rose Luther-Campise, MD, Enrico Benedetti, MD
    29.5 DONOR MORBIDITY AND MORTALITY 504
            Dianne LaPointe Rudow, DrNP, Milan Kinkhabwala, MD, Jean C. Emond, MD
    29.6 LONG-TERM DONOR OUTCOMES 513
            James F. Trotter, MD, Jeff Campsen, MD, Igal Kam, MD
    29.7 PSYCHOLOGICAL ASPECTS 518
            Roshan Shrestha, MD
CHAPTER 30 LIVER TRANSPLANTATION: THE RECIPIENT 522
    30.1  SELECTION AND WORKUP 522
             Henkie P. Tan, MD, PhD, Thomas Shaw-Stiffel, MD, Kusum Tom, MD, Amadeo
             Marcos, MD
    30.2  ANESTHESIOLOGIC CONSIDERATIONS 526
              Suzanne Shamsolkottabi, MD, Kumar G. Belani, MBBS, MS
    30.3   SURGICAL PROCEDURES 533
    30.4   OPTIMIZED VENOUS OUTFLOW 569
              Giuliano Testa, MD, Enrico Benedetti, MD
    30.5   ISCHEMIA AND REPERFUSION INJURY 572
              Sei-ichiro Tsuchihashi, MD, PhD, Fady Kaldas, MD, Ronald W. Busuttil, MD, PhD,
              Jerzy W. Kupiec-Weglinski, MD, PhD
    30.6   SMALL-FOR-SIZE GRAFTS 576
              Roberto Troisi, MD, PhD, Marleen Praet, MD, PhD, Bernard de Hemptinne MD, PhD
    30.7   PERIOPERATIVE CARE OF THE LIVER RECIPIENT 583
              Mark L. Sturdevant, MD, Ty Dunn, MD, Rainer W.G. Gruessner, MD
    30.8   POSTTRANSPLANT COMPLICATIONS 589
              Hiroyuki Furukawa, MD, Satoru Todo, MD
    30.9   INTERVENTIONAL THERAPIES 601
              Erik N.K. Cressman, MD, PhD
    30.10 IMMUNOSUPPRESSIVE THERAPY 605
              Roberto Gedaly, MD, Hosein Shokouh-Amiri, MD, Santiago R. Vera, MD, A. Osama
              Gaber, MD
    30.11 IMMUNOBIOLOGY 611
              Kenneth J. Woodside, MD, John A. Daller, MD, PhD
    30.12 CONTROVERSIAL INDICATIONS 617
    30.13 DOMINO LIVER TRANSPLANTATION 635
    30.14 LIVER RETRANSPLANTATION 643
    30.15 LONG-TERM OUTCOME 651
    30.16 STRATEGIES TO MAXIMIZE THE DONOR POOL 661
CHAPTER 31 LIVER TRANSPLANTATION: COST ANALYSIS 671
    Mark W. Russo, MD, MPH, Robert S. Brown, MD, MPH

SECTION IV INTESTINAL TRANSPLANTATION
CHAPTER 32 HISTORY OF LIVING DONOR INTESTINAL TRANSPLANTATION 678

    Rainer W.G. Gruessner, MD
CHAPTER 33 INTESTINAL TRANSPLANTATION – THE DONOR 685
    33.1 SELECTION AND WORKUP 685
            Enrico Benedetti, MD, Mark J. Holterman, MD, PhD, Giuliano Testa, MD
    33.2 SURGICAL PROCEDURES AND PERIOPERATIVE CARE 688
            Rainer W.G. Gruessner, MD
    33.3 MORBIDITY, MORTALITY, LONG-TERM OUTCOME 690
            Giuliano Testa, MD, Fabrizio Panaro, MD, Enrico Benedetti, MD
CHAPTER 34 INTESTINAL TRANSPLANTATION – THE RECIPIENT 694
    34.1 SELECTION AND WORKUP 694
            Enrico Benedetti, MD, Stefano DiDomenico, MD, Giuliano Testa, MD
    34.2 SURGICAL PROCEDURES AND PERIOPERATIVE CARE 699
            Rainer W.G. Gruessner, MD
    34.3 IMMUNOSUPPRESSIVE THERAPY AND POSTOPERATIVE COMPLICATION   705
            Enrico Benedetti, MD, Antonio Gangemi, MD, Giuliano Testa, MD
    34.4 PATHOLOGY OF SMALL BOWEL TRANSPLANTATION 711
            Jose Jessurun, MD, Stefan Pambuccian, MD
    34.5 REGISTRY REPORT AND LONG-TERM OUTCOME 714
            Shimul A. Shah, MD, David R. Grant, MD
    34.6 INTESTINAL TRANSPLANTION: COST ANALYSIS 718
            Giuliano Testa, MD, Aaron J. Simon, MHA, CHE, Enrico Benedetti, MD

PART IV: FUTURE DEVELOPMENTS AND ALTERNATIVES TO LIVING DONOR TRANSPLANTATION
CHAPTER 35 DUAL-ORGAN DONATION 723
    Rainer W.G. Gruessner, MD
CHAPTER 36 USE OF LIVING DONORS FOR HIV-POSITIVE TRANSPLANT 
CANDIDATES   725
    Peter G. Stock, MD, PhD
CHAPTER 37 NEW IMMUNOSUPPRESSIVE PROTOCOLS 731
    Rolf N. Barth, MD, Stuart J. Knechtle, MD
CHAPTER 38 STRATEGIES TO INDUCE TOLERANCE 737
    Gregor Warnecke, MD, Kathryn J. Wood, Dphil
CHAPTER 39 XENOTRANSPLANTATION 748
    Kazuhiko Yamada, MD, PhD, Prashanth Vallabhajosyula, MD, David H. Sachs, MD
CHAPTER 40 GENE THERAPY 760
    Jonathan S. Bromberg, MD, Peter Boros, MD, Nan Zhang, PhD
CHAPTER 41 ORGANOGENESIS AND CLONING 769
    Marilia Cascalho, MD, PhD, Brenda M. Ogle, PhD,  Jeffrey L. Platt, MD
INDEX 773
Color plates appear between pages 418 and 419.

  
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