Hormone therapy in breast and prostate cancer
Buku ini diterbitkan tahun 2002 Humana Press Inc. New Jersey adalah buku edisi Pertama.
Judul: Hormone therapy in breast and prostate cancer
Oleh: V. Craig Jordan, et al (Editor)
Penerbit: Humana Press Inc. New Jersey
Tahun: 2002
Jumlah Halaman: 423 hal.
Editor:
V. CRAIG JORDAN
Robert H. Lurie Comprehensive Cancer Center,
Northwestern University, Chicago, IL
BARRINGTON J. A. FURR
AstraZeneca Pharmaceuticals,
Macclesfield, UK
Lingkup Pembahasan:
Buku ini menggambarkan laboratorium dan pengembangan klinis konsep yang sekarang berhasil
diterapkan untuk pengobatan kanker payudara dan prostat. Buku ini adalah sebagai landasan dan panduan untuk kemajuan bagi para peneliti dan dokter. Kemajuan klinis selama tiga dekade terakhir tidak akan terjadi tapi untuk pergeseran konseptual dalam penalaran yang terjadi di awal 1970-an.
Daftar Isi:
Foreword by Elwood Jensen v
Preface vii
Contributors xiii
1 An Introduction to the Regulation of Sex Steroids for the Treatment of Cancer 1
V. Craig Jordan and Barrington J. A. Furr
Part I: Preclinical Antiestrogens
2 Antiestrogens and the Cell Cycle 17
Colin K. W. Watts, Owen W. J. Prall, Jason S. Carroll, Nicholas R. C. Wilcken, Eileen M. Rogan,
Elizabeth A. Musgrove, and Robert L. Sutherland
3 Drug Resistance to Antiestrogens 47
Ruth M. O'Regan, Anait S. Levenson, Gale M. England, Kathy A. Yao, Henry D. Muenzner,
Hiroyuki Takei, and V. Craig Jordan
4 Mechanisms of Liver Carcinogenesis by Antiestrogens 69
David H. Phillips
5 The Effects of Triphenylethylene Antiestrogens on Parameters of Multistage
Hepatocarcinogenesis in the Rat 83
Yvonne P. Dragan and Henry C. Pitot
6 Preclinical Studies of Raloxifene and Related Compounds 133
Robin Fuchs-Young
7 Pure Antiestrogens 161
Alan E. Wakeling
Part II: Antiestrogens: Clinical
8 Tamoxifen for the Treatment of Breast Cancer 185
V. Craig Jordan
9 Clinical Utility of New Antiestrogens 195
Ruth M. O'Regan and William J. Gradishar
10 Breast Cancer Prevention with Antiestrogens 213
Monica Morrow and V. Craig Jordan
Part III: Inhibition of Estrogen Synthesis
11 Aromatase Inhibitors 235
Paul E. Goss and Caroline C. Reid
12 Clinical Utility of Aromatase Inhibitors 265
K. Shenton, Mitchell Dowsett, and Michael Dukes
13 LH-RH Agonists for the Treatment of Breast Cancer: Development and Current
Status 293
Roger W. Blamey
Part IV: Androgens and Androgen Withdrawal
14 Molecular Action of Androgens 311
Shutsung Liao, Junichi Fukuchi, and Yung-Hsi Kao
15 Steroidal Antiandrogens 325
Fritz H. Schröder and Albert Radlmaier
16 Nonsteroidal Antiandrogens 347
Geert J. C. M. Kolvenbag and Barrington J. A. Furr
17 LH-RH Agonist Role in Prostate Cancer Management 369
Amir V. Kaisary
Part V: Perspective on Progress
18 Recent Progress in Breast Cancer Research 385
V. Craig Jordan and Barrington J. A. Furr
Index 409
Berminat?
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